Juergen Klopp returns to the scene of one his Liverpool side's most controversial victories of last season this Saturday with the man who fashioned it lining up against him.
Van Dijk was substituted early in the game when Everton goalkeeper Jordan Pickford made a reckless challenge in the box, which left Liverpool manager Juergen Klopp fuming.
Champions Liverpool were sent crashing out by Benfica.
Lukas Podolski and Olivier Giroud gave food for thought to Arsenal fans craving a new striker by scoring in a 3-1 Premier League win at Fulham on Saturday while Liverpool made it two victories from two games at Aston Villa.
Arsenal manager Arsene Wenger said he is still keen to sign Uruguayan striker Luis Suarez even though Liverpool have rejected two offers from the Gunners for him.
Klopp and his City counterpart Pep Guardiola were satisfied with their team's displays in a tight, tactical encounter which finished 0-0 at Anfield, but the German was clearly frustrated to now lose his players for international duty.
Liverpool went top of the Premier League on Monday after a goalless home draw with West Ham United.
Arsenal delivered a brutal lesson in fast-paced Premier League football to beat Liverpool 4-1 on Saturday, maintaining their faint title aspirations and almost certainly dashing their opponents' hopes of a top-four finish.
Arsenal goalkeeper Petr Cech believes that the Gunners need to stop silly losses against the teams they are expected to beat if they want to progress in the Premier League.
Two superb curling efforts from Jordan Henderson and Philippe Coutinho handed Liverpool a 2-1 home win against Manchester City in the Premier League on Sunday to deliver a thumping blow to Manuel Pellegrini's title aspirations.
Such is the impact Sadio Mane has made on Liverpool that the 24-year-old is an automatic pick to face Tottenham Hotspur in the Premier League on Saturday while experienced international teammates scrap it out to play alongside him.
Arsene Wenger acknowledged Southampton were the sharper team as they crushed Arsenal 4-0 on Saturday but he also blamed the defeat on bad luck.
Chelsea lost their 100 per cent Premier League record when London rivals West Ham United held them to a 0-0 draw on Sunday.
Chelsea brought a whole new dimension to the Premier League title race when they handed Manchester City their first defeat of the season on Saturday to leave Mohamed Salah-inspired Liverpool as the new leaders.
Luis Garcia scored twice in a 3-1 victory in the second leg of the Champions League pre-quarter-finals.
Liverpool captain Steven Gerrard has urged Luis Suarez to shun suitors Arsenal, saying a move to their Premier League rivals would not represent a step up for the unsettled Uruguayan.
While, Reds' manager Juergen Klopp is realistic about his team being league leaders, you, dear reader, can convey your opinion by casting your vote in the poll below
Liverpool will cover most miles of any Premier League club in pre-season preparation.
Arsenal midfielder Aaron Ramsey scored a contender for goal of the season when he blasted home a 30-metre volley to help his team cruise past Galatasaray 4-1 to finish second in Champions League Group D.
Liverpool snatched a 5-3 aggregate victory over Arsenal after late goals gave them a 4-2 win in the Champions League quarter-finals, while Chelsea scored a 2-0 home win over Turkish champions Fenerbahce to overturn a 2-1 first leg deficit.
Images from Saturday's action in the English Premier League.
Fernando Torres scored a hat-trick to inspire Liverpool to a 4-2 victory at Reading in the League Cup third round.
Mikel Arteta scored Premier League leaders Arsenal's first goal in a 2-0 win over Crystal Palace on Saturday but was later sent off in the early kickoff in south London.
Here is a look at the clubs most likely to give City a run for their money next season.
Manchester United moved into the top four for the first time this season with a scrappy 1-0 victory at Everton.
Liverpool were left frustrated by Championship side Blackburn Rovers who defended heroically to draw 0-0 at Anfield.
Former Arsenal, Spain midfielder Fabregas hangs up his boots, to coach Italian club.
Arsenal are brimming with confidence after beating Liverpool but they will have to show consistency to overcome in-form Porto in the Champions League last 16.
Images from the English Premier Lesgue matches played on Saturday.
Arsenal ended their seven match winless run in the Premier League with a surprise 3-1 London derby victory over Chelsea at the Emirates Stadium on Saturday while Manchester United were held to a 2-2 draw at Leicester City.
Liverpool suffered a shock 2-1 loss to Championship side Wolverhampton Wanderers in the FA Cup fourth round on Saturday, handing manager Juergen Klopp a third home defeat in a row.
Wenger's future at Arsenal will be decided after FA Cup final
European champions Liverpool made an emphatic start to the new Premier League season by scoring three times in the opening half an hour as they taught promoted Norwich City a harsh lesson with a 4-1 thrashing at Anfield on Friday.
The top four failed to muster a goal on Saturday as Chelsea, Liverpool and Manchester United drew 0-0 while Arsenal went down 3-0 at Manchester City. Premier League leaders Chelsea could find no way through Newcastle United at Stamford Bridge. Liverpool had the same problem at home to Fulham and third-placed Manchester United were held 0-0 in a lively game at Aston Villa.
Premier League leaders Manchester United sealed a needlessly nervy 2-1 home win over Liverpool on Sunday after Robin van Persie and Patrice Evra put rival Luis Suarez in the shade.
News of all that's transpired on and off the football field
Arsenal manager Arsene Wenger has reportedly given the green light to break the bank and spend 40 million pounds on controversial Liverpool striker Luis Suarez and the club is confident that Suarez will quit Liverpool for a sensational move to the Emirates.